Hello, Prilosec contains omeprazole and both pantoprazole and omeprazole belong to the same group. The drugs keep Plavix from working properly. The FDA warns patients on Plavix not to take Nexium or Prilosec -- or nine other drugs, including Prozac and Tagamet. No studies in patients with GERD demonstrate that the addition of histamine(2) receptor antagonists to twice-daily PPI therapy provides any further benefit above that derived from PPIs alone. Proton pump inhibitors (PPIs) have been associated with several severe, even life-threatening side effects when used frequently over an extended period of time. Your doctor may also suggest you take one at bedtime. These medications are not usually taken together. The over-the-counter dosage is 20mg whereas the prescription version is … It virtually eliminated peptic ulcer disease—or almost. The medication is available both over the counter and by prescription. Prilosec is the brand name for omeprazole, a protein pump inhibitor that is used to reduced the amount of acid in the stomach. St. John's wort, for example, should not be taken with these drugs. While this can help with the symptoms of heartburn whenever you eat a meal, it can decrease the absorption of your thyroid medication causing it not to work as well. Do not take any medicines on your own. So while it does not create a dangerous situation, the cefuroxime would not be as effective and possibly not effective. If a woman were taking an acid-suppressing drug such as esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec) or pantoprazole (Protonix) and then were tested for bone mineral density, she might be found to have osteopenia (early bone weakness) or osteoporosis. Of course—they are safe—but unless you have Zollinger Ellison Syndrome, there’s probably no reason. Examples of proton pump inhibitors include esomeprazole, pantoprazole, omeprazole, lansoprazole and rabeprazole. If pantoprazole is not helping you, you can take ranitidine or gelusil after consulting your gastroenterologist. Also included on the list of common prescriptions: proton pump inhibitors, such as Nexium and Prilosec. Does Pantoprazole SODIUM Interact with other Medications? The contraindication for taking cefuroxime while on omeprazole is because omeprazole decreases stomach acid which can significantly reduce the amount of cefuroxime in your system. Tips. The parameter used to measure the efficacy of combination regimens for GERD thus far--nocturnal acid breakth … These drugs, such as Prilosec (omeprazole), Nexium (esomeprazole), Prevacid (lansoprazole), and Protonix (pantoprazole), are used to treat acid reflux. Severe Interactions. Some of the most frequently prescribed medications in the U.S. are anxiety drugs. There are several brand names available over the counter. 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